NMDA and opioid receptors: their interactions in antinociception, tolerance and neuroplasticity
J Mao - Brain Research Reviews, 1999 - Elsevier
Over the last several years, significant progress has been made in our understanding of
interactions between the N-methyl-d-aspartate (NMDA) and opioid receptors. Such
interactions have been demonstrated at two distinct sites:(1) modulation of NMDA receptor-
mediated electrophysiological events by opioids; and (2) intracellular events involving
interactions between NMDA and opioid receptors. Furthermore, a considerable number of
studies have shown the involvement of such interactions in neural mechanisms of …
interactions between the N-methyl-d-aspartate (NMDA) and opioid receptors. Such
interactions have been demonstrated at two distinct sites:(1) modulation of NMDA receptor-
mediated electrophysiological events by opioids; and (2) intracellular events involving
interactions between NMDA and opioid receptors. Furthermore, a considerable number of
studies have shown the involvement of such interactions in neural mechanisms of …
