Immune changes in HIV-1 infection: significant correlations and differences in serum markers and lymphoid phenotypic antigens

HZ Bass, P Nishanian, WD Hardy, RT Mitsuyasu… - Clinical immunology and …, 1992 - Elsevier
Human immunodeficiency virus type 1 (HIV-1) induces extensive immune cell alterations
which can be detected by changes both in serum levels of soluble immune activation
products and in several lymphoid phenotypic markers. The current studies were conducted
in 70 HIV-1 seropositive subjects to determine whether changes among four important
serum immune activation markers (neopterin, β-2 microglobulin, soluble CD8, and soluble IL-
2 receptor) and seven lymphoid phenotypic markers (CD38, HLA-DR, CD57, CD11b …