Increased circulating plasma norepinephrine concentrations in noncardiac causes of pulmonary hypertension
GP ZALOGA, B CHERNOW, JR FLETCHER… - Critical Care …, 1984 - journals.lww.com
Sympathetic nervous system (SNS) activity and circulating norepinephrine (NE) levels may
play roles in the elevated pulmonary vascular resistance (PVR) found in patients with
pulmonary hypertension. To study the relationship between plasma NE levels, pulmonary
NE metabolism, and pulmonary hypertension, we studied 9 patients, suspected of having
noncardiac causes of pulmonary hypertension, before and after vasodilator therapy with
phentolamine, nitroglycerin, oproterenol, or hydralazine. Patients were admitted to the ICU …
play roles in the elevated pulmonary vascular resistance (PVR) found in patients with
pulmonary hypertension. To study the relationship between plasma NE levels, pulmonary
NE metabolism, and pulmonary hypertension, we studied 9 patients, suspected of having
noncardiac causes of pulmonary hypertension, before and after vasodilator therapy with
phentolamine, nitroglycerin, oproterenol, or hydralazine. Patients were admitted to the ICU …