Remission of idiopathic hypoparathyroidism during lactation: a case report

T Anai, T Tomiyasu, N Takai… - Journal of Obstetrics and …, 1999 - Wiley Online Library
T Anai, T Tomiyasu, N Takai, I Miyakawa
Journal of Obstetrics and Gynaecology Research, 1999Wiley Online Library
A 35‐year‐old woman with idiopathic hypoparathyroidism achieved a spontaneous
remission during lactation even though 1‐α‐hydroxyvitamin D3 therapy was discontinued
after delivery. Urinary excretion of cyclic adenosine 3′, 5′‐monophosphate and
phosphate was significantly increased during lactation, probably in response to the
increased levels of circulating parathyroid hormone‐related protein derived from the breast
tissue.
Abstract
A 35‐year‐old woman with idiopathic hypoparathyroidism achieved a spontaneous remission during lactation even though 1‐α‐hydroxyvitamin D3 therapy was discontinued after delivery. Urinary excretion of cyclic adenosine 3′,5′‐monophosphate and phosphate was significantly increased during lactation, probably in response to the increased levels of circulating parathyroid hormone‐related protein derived from the breast tissue.
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