The cellular basis of skin injury after cytotoxic insult.
CS Potten - The British Journal of cancer. Supplement, 1986 - ncbi.nlm.nih.gov
CS Potten
The British Journal of cancer. Supplement, 1986•ncbi.nlm.nih.govThe skin is one of the larger organs of the body covering a surface area of about 2m2 in man
and about 0.008 m2 in the mouse and weighing about 2.1 kg and 3.3 g respectively. It
provides a continuous protective outer sheath to the body and extends into the various
orificesto maintain a continuous covering of oral, respiratory, gastro-intestinal, anal and
urino-genital epithelium. Hence to some extent consideration of structure, function and their
impairment by cytotoxic factors overlap for these internal and external epithelia.
and about 0.008 m2 in the mouse and weighing about 2.1 kg and 3.3 g respectively. It
provides a continuous protective outer sheath to the body and extends into the various
orificesto maintain a continuous covering of oral, respiratory, gastro-intestinal, anal and
urino-genital epithelium. Hence to some extent consideration of structure, function and their
impairment by cytotoxic factors overlap for these internal and external epithelia.
The skin is one of the larger organs of the body covering a surface area of about 2m2 in man and about 0.008 m2 in the mouse and weighing about 2.1 kg and 3.3 g respectively. It provides a continuous protective outer sheath to the body and extends into the various orificesto maintain a continuous covering of oral, respiratory, gastro-intestinal, anal and urino-genital epithelium. Hence to some extent consideration of structure, function and their impairment by cytotoxic factors overlap for these internal and external epithelia.
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