Proliferating cell nuclear antigen staining in syndrome and nonsyndrome odontogenic keratocysts
A El Murtadi, D Grehan, M Toner… - Oral Surgery, Oral …, 1996 - Elsevier
OBJECTIVES.: The relatively aggressive behavior of the odontogenic keratocyst might be
expected to correlate with the degree of proliferation of the cyst epithelium. The proliferation
rate of odontogenic keratocyst epithelium was studied with the use of an antibody to the
proliferating cell nuclear antigen, a nuclear protein expressed in cycling cells. STUDY
DESIGN.: We used the monoclonal antibody PC10 to examine 41 odontogenic keratocysts
(21 associated with the nevoid basal cell carcinoma syndrome, 20 nonsyndrome), and …
expected to correlate with the degree of proliferation of the cyst epithelium. The proliferation
rate of odontogenic keratocyst epithelium was studied with the use of an antibody to the
proliferating cell nuclear antigen, a nuclear protein expressed in cycling cells. STUDY
DESIGN.: We used the monoclonal antibody PC10 to examine 41 odontogenic keratocysts
(21 associated with the nevoid basal cell carcinoma syndrome, 20 nonsyndrome), and …
