[PDF][PDF] STUDIES OF UREA EXCRETION. II: Relationship Between Urine Volume and the Rate of Urea Excretion by Normal Adults
E Möller, JF McIntosh… - The Journal of clinical …, 1928 - Am Soc Clin Investig
E Möller, JF McIntosh, DD Van Slyke
The Journal of clinical investigation, 1928•Am Soc Clin InvestigUREA EXCRETION tion limit, urea excretion proceeds at maximum speed, and the output
per minute represents the urea content of a maximum blood volume. This blood volume,
averaging in normal men about 75 cc. per minute, we shall for convenience term the
maximum blood urea clearance, or simply the maximum clearance. It represents the volume
of blood which one minute's excretion suffices to clear of urea when the urine volume is
large enough to permit a maximum urea output. The value of the maximum clearance, Cm, is …
per minute represents the urea content of a maximum blood volume. This blood volume,
averaging in normal men about 75 cc. per minute, we shall for convenience term the
maximum blood urea clearance, or simply the maximum clearance. It represents the volume
of blood which one minute's excretion suffices to clear of urea when the urine volume is
large enough to permit a maximum urea output. The value of the maximum clearance, Cm, is …
UREA EXCRETION tion limit, urea excretion proceeds at maximum speed, and the output per minute represents the urea content of a maximum blood volume. This blood volume, averaging in normal men about 75 cc. per minute, we shall for convenience term the maximum blood urea clearance, or simply the maximum clearance. It represents the volume of blood which one minute's excretion suffices to clear of urea when the urine volume is large enough to permit a maximum urea output. The value of the maximum clearance, Cm, is calculated from the observed urea concentrations of the blood and urine, B and U, and the urine volume, V, in cubic centimeters per minute, by the formula,
The Journal of Clinical Investigation