Disturbances in the composition of plasma lipoproteins during gram-negative sepsis in the rat

S Lanza-Jacoby, SH Wong, A Tabares, D Baer… - … et Biophysica Acta (BBA …, 1992 - Elsevier
Hyperlipidemia is associated with gram-negative sepsis. In this study we characterized the
plasma lipoproteins of fasted and fed septic and control rats with respect to their lipid and
apolipoprotein composition. Sepsis was induced by iv injection of 8× d 10 7 live Eschericia
coli colonies/100 g body wt. Food was removed from fasted control and fasted E. coli-treated
rats after injection. Fed rats were infused intragastrically with a nutritionally complete diet for
5 days prior to E. coli treatment. 24 h after treatment with E. coli, lipid and protein …