Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different
tissues and therefore may have both endocrine and paracrine effects. Ghrelin is the
endogenous ligand of the G protein-coupled growth hormone secretagogue receptor. In the
current review we comprehensively summarize (i) the data available regarding the structure,
expression pattern and regulation of ghrelin and its receptor;(ii) the available information …