[HTML][HTML] Transcriptional regulation of the hepatocyte growth factor gene by the nuclear receptors chicken ovalbumin upstream promoter transcription factor and …
JG Jiang, A Bell, Y Liu, R Zarnegar - Journal of Biological Chemistry, 1997 - ASBMB
Hepatocyte growth factor (HGF) is a multifunctional cytokine that controls the growth and
differentiation of various tissues. Previously, we described the existence of a negative cis-
acting regulatory element (s) within the− 1-to− 0.7-kilobase pair (kb) portion of the 5′-
flanking region of the mouse HGF promoter. In the present study, we show that the repressor
element is located at position− 872 to− 860 base pairs and comprises an imperfect estrogen-
responsive element 5′-AGGTCAGAAAGACCA-3′. We demonstrate that chicken …
differentiation of various tissues. Previously, we described the existence of a negative cis-
acting regulatory element (s) within the− 1-to− 0.7-kilobase pair (kb) portion of the 5′-
flanking region of the mouse HGF promoter. In the present study, we show that the repressor
element is located at position− 872 to− 860 base pairs and comprises an imperfect estrogen-
responsive element 5′-AGGTCAGAAAGACCA-3′. We demonstrate that chicken …
