[HTML][HTML] Poly (ADP-ribose) polymerase is a B-MYB coactivator
MN Cervellera, A Sala - Journal of Biological Chemistry, 2000 - ASBMB
B-MYB is implicated in cell growth control, differentiation, and cancer and belongs to the
MYB family of nuclear transcription factors. Evidence exists that cellular proteins bind directly
to B-MYB, and it has been hypothesized that B-MYB transcriptional activity may be
modulated by specific cofactors. In an attempt to isolate proteins that interact with the B-MYB
DNA-binding domain, a modular domain that has the potential to mediate protein-protein
interaction, we performed pull-down experiments with a glutathione S-transferase-B-MYB …
MYB family of nuclear transcription factors. Evidence exists that cellular proteins bind directly
to B-MYB, and it has been hypothesized that B-MYB transcriptional activity may be
modulated by specific cofactors. In an attempt to isolate proteins that interact with the B-MYB
DNA-binding domain, a modular domain that has the potential to mediate protein-protein
interaction, we performed pull-down experiments with a glutathione S-transferase-B-MYB …
