Glucose suppresses basal firing and haloperidol-induced increases in the firing rate of central dopaminergic neurons

CF Saller, LA Chiodo - Science, 1980 - science.org
CF Saller, LA Chiodo
Science, 1980science.org
In the rat, doses of glucose sufficient to raise glucose concentrations in the blood to levels
equivalent to those produced by a meal or stress suppress the firing of dopamine-containing
neurons located within the substantia nigra. Glucose also prevents or reverses the increase
in discharge rates of dopaminergic cells normally elicited by the antipsychotic agent
haloperidol.
In the rat, doses of glucose sufficient to raise glucose concentrations in the blood to levels equivalent to those produced by a meal or stress suppress the firing of dopamine-containing neurons located within the substantia nigra. Glucose also prevents or reverses the increase in discharge rates of dopaminergic cells normally elicited by the antipsychotic agent haloperidol.
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