Antiviral IFN-γ responses of monocytes at birth predict respiratory tract illness in the first year of life
K Sumino, J Tucker, M Shahab, KF Jaffee… - Journal of allergy and …, 2012 - Elsevier
BACKGROUND: Viral respiratory tract infections are the leading cause of acute illness
during infancy and are closely linked to chronic inflammatory airway diseases later in life.
However, the determinants of susceptibility to acute respiratory tract infections still need to
be defined. OBJECTIVE: We investigated whether the individual variation in antiviral
response at birth determines the risk for acute respiratory tract illness in the first year of life.
METHODS: We studied 82 children who were enrolled in a birth cohort study of inner-city …
during infancy and are closely linked to chronic inflammatory airway diseases later in life.
However, the determinants of susceptibility to acute respiratory tract infections still need to
be defined. OBJECTIVE: We investigated whether the individual variation in antiviral
response at birth determines the risk for acute respiratory tract illness in the first year of life.
METHODS: We studied 82 children who were enrolled in a birth cohort study of inner-city …