Inappropriate or excessive pulmonary inflammation can contribute to chronic lung diseases.
In health, the resolution of inflammation is an active process that terminates inflammatory
responses. The recent identification of endogenous lipid-derived mediators of resolution has
provided a window to explore the pathobiology of inflammatory disease and structural
templates for the design of novel pro-resolving therapeutics. Resolvins (resolution-phase
interaction products) are a family of pro-resolving mediators that are enzymatically …