[HTML][HTML] Analysis of malaria parasite phenotypes using experimental genetic crosses of Plasmodium falciparum
LC Ranford-Cartwright, JM Mwangi - International journal for parasitology, 2012 - Elsevier
We review the principles of linkage analysis of experimental genetic crosses and their
application to Plasmodium falciparum. Three experimental genetic crosses have been
performed using the human malaria parasite P. falciparum. Linkage analysis of the progeny
of these crosses has been used to identify parasite genes important in phenotypes such as
drug resistance, parasite growth and virulence, and transmission to mosquitoes. The
construction and analysis of genetic maps has been used to characterise recombination …
application to Plasmodium falciparum. Three experimental genetic crosses have been
performed using the human malaria parasite P. falciparum. Linkage analysis of the progeny
of these crosses has been used to identify parasite genes important in phenotypes such as
drug resistance, parasite growth and virulence, and transmission to mosquitoes. The
construction and analysis of genetic maps has been used to characterise recombination …
