Reductions in mesolimbic responsivity have been noted following Roux-en-Y gastric bypass
(RYGB; Ochner et al., 2011a). Given potential for postoperative increases in postprandial gut
(satiety) peptides to affect mesolimbic neural responsivity, we hypothesized that:(1) post
RYGB changes in mesolimbic responsivity would be greater in the fed relative to the fasted
state and;(2) fasted vs. fed state differences in mesolimbic responsivity would be greater
post-relative to pre-surgery. fMRI was used to asses neural responsivity to high-and low …