In vitro development of infectious liver stages of P. yoelii and P. berghei malaria in human cell lines
JM Calvocalle, A Moreno, WMC Eling… - Experimental …, 1994 - Elsevier
The preerythrocytic stages of the malaria parasite are the focus of intense efforts to identify
new immunological and pharmacological methods for the control of the malaria parasite.
The study of the malaria hepatic stages requires an in vitro system to facilitate the analysis of
parasite/host cell interactions and the characterization of exoerythrocytic form (EEF)
antigens. At the present time, only the rodent malaria, Plasmodium berghei, and the human
malaria, Plasmodium vivax, develop into mature infectious EEF within established cell lines …
new immunological and pharmacological methods for the control of the malaria parasite.
The study of the malaria hepatic stages requires an in vitro system to facilitate the analysis of
parasite/host cell interactions and the characterization of exoerythrocytic form (EEF)
antigens. At the present time, only the rodent malaria, Plasmodium berghei, and the human
malaria, Plasmodium vivax, develop into mature infectious EEF within established cell lines …