Extra-oral bitter taste receptors: New targets against obesity?
Q Wang, KI Liszt, I Depoortere - Peptides, 2020 - Elsevier
Taste perception on the tongue is essential to help us to identify nutritious or potential toxic
food substances. Emerging evidence has demonstrated the expression and function of bitter
taste receptors (TAS2Rs) in a wide range of extra-oral tissues. In particular, TAS2Rs in
gastrointestinal enteroendocrine cells control the secretion of appetite regulating gut
hormones and influence hunger and food intake. Furthermore, these effects may be
reinforced by the presence of TAS2Rs on intestinal smooth muscle cells, adipocytes and the …
food substances. Emerging evidence has demonstrated the expression and function of bitter
taste receptors (TAS2Rs) in a wide range of extra-oral tissues. In particular, TAS2Rs in
gastrointestinal enteroendocrine cells control the secretion of appetite regulating gut
hormones and influence hunger and food intake. Furthermore, these effects may be
reinforced by the presence of TAS2Rs on intestinal smooth muscle cells, adipocytes and the …
