Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints
them with a variety of inflammatory processes. For example, platelets can act as circulating
sentinels by expressing Toll-like receptors (TLR) that bind pathogens and this allows
platelets to effectively kill them or present them to cells of the immune system. Furthermore,
activated platelets secrete and express many pro-and anti-inflammatory molecules that
attract and capture circulating leukocytes and direct them to inflamed tissues. In addition …