Diseases (AASLD) also presented and continued to revise their clinical practice guidelines, and the latest updates were in 2015, 2017, and 2018. However, since the medical environment in each country is somewhat different depending on race, region, institution, and economic conditions, it is necessary to revise the Korean guidelines to reflect our medical environment and research results. The clinical practice guidelines committee has begun revising guidelines to reflect the results of Korean and international research published since the revision of the KASL clinical practice guidelines for management of CHB in 2015 and to develop new recommendations. In particular, recent information on newly available antiviral agents has been added, and the goals and the aims of treatment as well as starting and cessation of treatment have been clearly defined. The present guidelines also summarize updates for management of drug resistance, partial virological response, and side effects. In addition, additional data on the topics of epidemiology, prevention, natural history, diagnosis, monitoring, and management of CHB in specific situations are reflected in this update. Expert opinions were solicited in cases of insufficient data to make definitive conclusions. However, as the guidelines do not represent a standard treatment protocol, clinicians should keep in mind that the best management may vary depending on the individual patient.