Positron emission tomography greatly advanced our understanding on the underlying
neural mechanisms of movement disorders. PET with flurodeoxyglucose (FDG) is especially
useful as it depicts regional metabolic activity level that can predict patients' symptoms.
Multivariate pattern analysis has been used to determine and quantify the co-varying brain
networks associated with specific clinical traits of neurodegenerative disease. The result is a
biomarker, useful for diagnosis, treatments, and follow up studies. Parkinsonian traits and …