[PDF][PDF] Risk difference of liver-related and cardiovascular events by liver fibrosis status in nonalcoholic fatty liver disease

N Tamaki, M Higuchi, M Kurosaki, R Loomba… - Clinical …, 2022 - Elsevier
N Tamaki, M Higuchi, M Kurosaki, R Loomba, N Izumi, K Inada, S Kirino, K Yamashita…
Clinical Gastroenterology and Hepatology, 2022Elsevier
Nonalcoholic fatty liver disease (NAFLD) has affected more than one-fourth of the global
population, thus emerging as a worldwide health and economic burden. 1 The common
causes of death in patients with NAFLD include cardiovascular disease (CVD),
decompensation, and hepatocellular carcinoma (HCC). However, identifying the risk of
these complications in patients with NAFLD remains an unmet need in clinical practice.Liver
fibrosis is significantly associated with mortality risk in NAFLD, 2 and a significant …
Nonalcoholic fatty liver disease (NAFLD) has affected more than one-fourth of the global population, thus emerging as a worldwide health and economic burden. 1 The common causes of death in patients with NAFLD include cardiovascular disease (CVD), decompensation, and hepatocellular carcinoma (HCC). However, identifying the risk of these complications in patients with NAFLD remains an unmet need in clinical practice.
Liver fibrosis is significantly associated with mortality risk in NAFLD, 2 and a significant association between magnetic resonance elastography (MRE) and liver fibrosis has been reported. However, the association between MRE and complication incidence (HCC, decompensation, and CVD) remains unclear. Hence, in this study, we investigated the association between MRE and the development of HCC, decompensation, and CVD in patients with NAFLD.
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