Sweet's syndrome: is the pathogenesis mediated by helper T cell type 1 cytokines?
ASM Giasuddin, AHAM El-Orfi, MM Ziu… - Journal of the American …, 1998 - Elsevier
Background: The pathogenesis of Sweet's syndrome (acute febrile neutrophilic dermatosis;
SS) is still not fully understood. An imbalance between helper T cell types 1 and 2 cytokine
secretion patterns has been shown to be relevant in many diseases. Objective: We
assessed the serum cytokine levels (interleukin [IL]-1α, IL-1β, IL-2, interferon gamma [IFN-γ],
IL-4) in patients with SS. Methods: Eight patients with SS were analyzed for their clinical
features and serum cytokine levels and compared with normal control subjects. Results: In …
SS) is still not fully understood. An imbalance between helper T cell types 1 and 2 cytokine
secretion patterns has been shown to be relevant in many diseases. Objective: We
assessed the serum cytokine levels (interleukin [IL]-1α, IL-1β, IL-2, interferon gamma [IFN-γ],
IL-4) in patients with SS. Methods: Eight patients with SS were analyzed for their clinical
features and serum cytokine levels and compared with normal control subjects. Results: In …