[HTML][HTML] ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated …
A Agaimy, K Erlenbach-Wünsch, B Konukiewitz… - Modern Pathology, 2013 - Elsevier
The human insulin gene enhancer-binding protein islet-1 (ISL1) is a transcription factor
involved in the differentiation of the neuroendocrine pancreatic cells. Recent studies
identified ISL1 as a marker for pancreatic well-differentiated neuroendocrine neoplasms.
However, little is known about ISL1 expression in pancreatic poorly differentiated and in
extrapancreatic well and poorly differentiated neuroendocrine neoplasms. We studied the
immunohistochemical expression of ISL1 in 124 neuroendocrine neoplasms. Among …
involved in the differentiation of the neuroendocrine pancreatic cells. Recent studies
identified ISL1 as a marker for pancreatic well-differentiated neuroendocrine neoplasms.
However, little is known about ISL1 expression in pancreatic poorly differentiated and in
extrapancreatic well and poorly differentiated neuroendocrine neoplasms. We studied the
immunohistochemical expression of ISL1 in 124 neuroendocrine neoplasms. Among …