Tau-targeting antibody therapies: too late, wrong epitope or wrong target?

E Jabbari, KE Duff - Nature Medicine, 2021 - nature.com
Nature Medicine, 2021nature.com
Tau-targeting antibody therapies: too late, wrong epitope or wrong target? | Nature
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Two phase 2 studies of N-terminal tau–targeting antibody therapy fail to show clinical efficacy in progressive supranuclear palsy, despite evidence of target engagement.
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