[HTML][HTML] First report from the German COVID-19 autopsy registry

S von Stillfried, RD Bülow, R Röhrig, P Boor… - The Lancet Regional …, 2022 - thelancet.com
S von Stillfried, RD Bülow, R Röhrig, P Boor, J Böcker, J Schmidt, P Tholen, R Majeed
The Lancet Regional Health–Europe, 2022thelancet.com
Background Autopsies are an important tool in medicine, dissecting disease
pathophysiology and causes of death. In COVID-19, autopsies revealed eg, the effects on
pulmonary (micro) vasculature or the nervous system, systemic viral spread, or the interplay
with the immune system. To facilitate multicentre autopsy-based studies and provide a
central hub supporting autopsy centres, researchers, and data analyses and reporting, in
April 2020 the German COVID-19 Autopsy Registry (DeRegCOVID) was launched. Methods …
Summary
Background Autopsies are an important tool in medicine, dissecting disease pathophysiology and causes of death. In COVID-19, autopsies revealed eg, the effects on pulmonary (micro) vasculature or the nervous system, systemic viral spread, or the interplay with the immune system. To facilitate multicentre autopsy-based studies and provide a central hub supporting autopsy centres, researchers, and data analyses and reporting, in April 2020 the German COVID-19 Autopsy Registry (DeRegCOVID) was launched.
Methods The electronic registry uses a web-based electronic case report form. Participation is voluntary and biomaterial remains at the respective site (decentralized biobanking). As of October 2021, the registry included N= 1129 autopsy cases, with 69271 single data points including information on 18674 available biospecimens gathered from 29 German sites.
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