In this episode, Yijuang Chern and Jian Jing Siew discuss the novel role of Gal3 in the regulation of extracellular vesicles, promotion of pathogenic tau fibrillation, and microglial activation.
In this episode, Eralda Kina and Claude Perreault explain how using proteogenomics, their manuscript identifies tumor-specific antigens in primary human breast cancers. These antigens are more numerous in triple-negative tumors and represent attractive targets for immunotherapy.
In this episode, Xiaobo Wang, Shuang Geng, and Junchen Meng explain how this work reestablished the suppressive functions in Tconvs absence of Foxp3 indistinguishable from Tregs by simply blocking RyR2 expression.
In this episode, Kumar Sharma explains that urine adenine/creatinine is a marker for kidney failure in patients with diabetes, and endogenous adenine plays a potential causative role in diabetic kidney disease.
A committed champion of vaccines and vaccine diplomacy, Dr. Peter Hotez is the Dean of the National School of Tropical Medicine and Professor of Pediatrics and Molecular Virology and Microbiology at the Baylor College of Medicine. As codirector of the Texas Children’s Hospital Center for Vaccine Development, Hotez has led the development and clinical trials of low-cost vaccines for hookworm infection, schistosomiasis, leishmaniasis, Chagas disease, and various coronaviruses. His persistence in the face of online and in-person harassment is impressive. This is an interview with Dr. Hotez from a stop on his book tour at Memorial Sloan Kettering Cancer Center on September 20, 2023.