PET allows noninvasive imaging of a variety of events in the body, including the activity of neuronal circuits in the brain that are involved in cognition and behaviors, by using radiotracers that detect relevant biological reactions. A major impediment to expanding PET applications to study the brain has been the lack of radiotracers that can identify and measure specific types of neurons or glial cells. In this issue of the
Helene Benveniste, Yuri Lazebnik, Nora D. Volkow
In this issue, Van de Bittner and colleagues describe a PET radiotracer that has the potential to allow visualization of OSN formation and turnover.